Artificial blood vessels made from salmon skin

12 Mar 2007

Artificial blood vessels made from salmon skin --- Researchers from Hokkaido University have created artificial blood vessels using collagen derived from the skin of salmon. The researchers, who replaced the aortas of rats with the artificial blood vessels, claim to be the first to create and successfully test artificial blood vessels made using collagen derived from marine animals.

The researchers decided to use salmon skin for regenerative medicine applications after seeing large amounts of the skin go to waste in local seafood processing operations. On Japan's northern island of Hokkaido, seafood processors discard about 2,000 tons of salmon skin each year -- enough to yield an estimated 600 tons of collagen. In addition, there are no known viruses transmitted from salmon to humans, so the use of salmon collagen is regarded as relatively safe. Scientists have created artificial tissue from bovine (cow) and porcine (pig) collagen in the past, but there have always been concerns over the possible transmission of infectious diseases such as BSE (mad cow disease).

One problem the researchers faced early on was the salmon collagen's poor resistance to heat. Because salmon collagen ordinarily melts at about 19 degrees Celsius (66 degrees Fahrenheit), it could not be used as a tissue replacement in humans. But by developing a process that forms the collagen into fibers and strengthens the bonds between molecules, the researchers were able to raise the melting point of the collagen to 55 degrees Celsius (131 degrees Fahrenheit).

The heat-resistant collagen was used to create blood vessels with an internal diameter of 1.6 mm and a wall thickness of 0.6 mm. When grafted into rats, the artificial blood vessels demonstrated the ability to expand and contract along with the heartbeat, and they were shown to be as strong and elastic as the original aortas.

Nobuhiro Nagai, from Hokkaido University, says the researchers plan to test the blood vessels in larger animals such as dogs. One day they hope to see their biomaterial used in humans as a replacement for damaged blood vessels, he says.

The research results are set to be announced at a meeting of the Japanese Society for Regenerative Medicine (JSRM), which is scheduled to begin in Yokohama on March 13.

[Source: Mainichi]

Video: Tremoctopus defense mechanism

07 Mar 2007

Palmate octopus --- Most octopi squirt thick clouds of black ink to confuse predators. This video from a Japanese TV quiz show, however, shows a type of Tremoctopus, or blanket octopus (murasakidako in Japanese), employing a different technique.

The video explains that when threatened, the octopus unfurls a giant sheet of webbing that trails behind like a cape. The webbing breaks apart rather easily when attacked -- much like a lizard's tail -- and it gets wrapped around the predator's face, giving the octopus a chance to flee.

Smart car seat detects drowsy drivers

05 Mar 2007

Smart seat --- Researchers from the University of Tokyo, Oita University, the Shimane Institute of Health Science and Delta Tooling, an industrial equipment manufacturer, have developed a prototype smart car seat capable of detecting when its occupant is on the verge of falling asleep. The seat was unveiled at a symposium held at the University of Tokyo on February 5.

The researchers began by studying the physiological signs of 100 sleepy subjects, focusing particularly on the changes in pulse and respiration that occur 10 minutes before falling asleep. They then developed a system of sensors that could both detect these changes and be embedded in the seat.

The seat is equipped with a pair of pulse-monitoring pressure sensors in the seat-back and a set of respiration-monitoring sensors underneath. The researchers successfully tested the system in a variety of simulated and actual driving conditions, and they claim it works effectively even when the driver is bundled in layers of clothing.

Previous drowsiness prediction systems that rely on physiological data require the subject to attach electrodes or other hardware to his or her body. And since these systems tend to be bulky, they have not seen widespread use in automobiles. However, unlike previous systems, this newly developed smart car seat does not require the driver to wear any special hardware -- it can detect drowsiness as long as the driver remains in the seat.

Though the seat can sense when the driver is sleepy, it is not yet equipped to respond. The next step will be to outfit the seat with an alarm function that is automatically activated when its occupant becomes drowsy. The researchers hope to make the smart seat commercially available in 5 years.

[Sources: Asahi, Yomiuri, University of Tokyo press release (PDF)]

Edo-period kappa sketches

02 Mar 2007

Kappa --- Kappa, arguably Japan's most well-known creature of legend, are mischievous river imps notorious for luring people -- particularly children -- into the water to drown and eat them. They smell like fish, enjoy cucumbers and sumo, and are said to be very courteous despite their malicious tendencies.

Although kappa are typically about the size of a child and greenish in color, they can vary widely in appearance. They frequently have a turtle-like shell and scaly skin, but sometimes their skin is moist and slick, or coated in fur. Most walk upright on their hind legs, but they are occasionally seen on all fours. Regardless of body type, the top of the kappa's head usually features a bowl-shaped depression containing water. The water inside this bowl is the source of the kappa's power.

The Edo period (1603 to 1867) saw some serious scientific literature devoted to the study of these creatures. Suikokouryaku (1820), for example, is a compendium of kappa-related information gathered from a variety of sources from Japan and China. The book, which is housed in the Iwase Bunko Library, includes kappa sketches by artist Kurimoto Tanshu. Here are a few.

Kappa ---

The kappa on the left, sketched by Ito Chobei, was captured during the Meiwa period (1764 to 1772) in Edo, somewhere in present-day Tokyo's Edogawa ward. When the creature was shown to Ota Chogen, a noted herbalist of the time, he identified it as a kappa -- he happened to have a kappa sketch with him that showed a creature with strikingly similar features. According to the text in the book, this kappa measured 60 cm (2 ft) tall and had slippery skin like that of a catfish.

The middle picture above shows a type of kappa with no shell, and the picture on the right shows a kappa that was caught in a net in Mito, Japan in 1801. This kappa had a prominent chest, a crooked back and three anuses.

Kappa ---

Later in the Edo period, an illustrated guide to 12 types of kappa (Suiko juni-hin no zu) was produced based on information taken from Suikokouryaku. A portion of this document is shown above. Check out the complete, high-resolution version here.

Kappa --- Kappa --- Kappa ---

Ito Keisuke, a well-known man of medicine and prolific natural history artist in the Edo period, sometimes included depictions of mysterious creatures with his animal drawings -- like the kappa on the left above, for example. The middle picture shows a kappa that was observed in one of the moats around Edo castle in the late 18th century. The picture on the right shows a kappa observed in the early 17th century in what is now the city of Hita in Oita prefecture (Kyushu). This kappa looked sort of like a turtle standing on its hind legs, and it had a depression on its head, webbed fingers, and splotches on its chest and abdomen.

Kappa --- Kappa ---

The neneko (or neko) kappa, shown on the left above, was sketched by Akamatsu Sotan in his 1855 work entitled Tonegawa zushi ("Illustrated History of the Tone River"). This kappa was known to move to a new location along the river each year, causing trouble wherever it went.

The image on the right shows a kappa scroll and kappa hand belonging to Sougenji (a.k.a. Kappa-dera, or "kappa temple") located in the Ueno-Asakusa area of Tokyo. The temple is one of countless places in Japan that has stories and legends of kappa associated with it. According to this temple's legend, the surrounding area was once a basin with poor drainage, making it prone to flooding. A local raincoat maker (the Japanese word for "raincoat" is "kappa") took it upon himself to construct a series of drainage ditches, which he was able to complete with the help of a kappa living in the Sumida River. It is said that people fortunate enough to lay eyes on this kappa were blessed with success in business.

For lots more background information and kappa links, check here.

Sushi – The Japanese Tradition

28 Feb 2007

Sushi culture is mysterious and the etiquette complex, but fortunately we have this entertaining video by Japan Culture Lab to explain it all. A must-see for anyone who has ever wondered why Japanese feet smell like vinegar.

Tiny robot reduces need for surgery

26 Feb 2007

Surgical microbot ---

On February 26, researchers from Ritsumeikan University and the Shiga University of Medical Science completed work on a miniature robot prototype that, once inserted into the body through an incision, can be freely controlled to perform medical treatment and capture images of affected areas. The plastic-encased minibot, which measures 2 cm (0.8 inch) in length and 1 cm (0.4 inch) in diameter, can be maneuvered through the body by controlling an external magnetic field applied near the patient.

While other types of miniature swallowable robots have been developed in the past, their role has mostly been limited to capturing images inside the body. According to Ritsumeikan University professor Masaaki Makikawa, this new prototype robot has the ability to perform treatment inside the body, eliminating the need for surgery in some cases.

The researchers developed five different kinds of prototypes with features such as image capture functions, medicine delivery systems, and tiny forceps for taking tissue samples. MRI images of the patient taken in advance serve as a map for navigating the minibot, which is said to have performed swimmingly in tests on animals. Sensor and image data is relayed back to a computer via an attached 2-mm diameter cable, which looks like it can also serve as a safety line in case the minibot gets lost or stranded.

[Source: Chugoku Shimbun]

Videos by Koichiro Tsujikawa (+ Cornelius)

26 Feb 2007

Koichiro Tsujikawa is a self-taught video artist who began as a graphic designer and visual producer for live concerts. Here are a few of his surreal works...

- Untitled (2004): This short film about an alien athlete was commissioned by Panasonic for the 2004 Olympics.

- Eyes (2004): This video was commissioned by Getty Images as part of The Big Idea, where filmmakers created short pieces from Getty Images content (check the link for other cool shorts). Soundtrack by Cornelius.

- Fit Song - Cornelius (2006): Household objects go crazy when stop-motion video meets computer animation. From the album "Sensuous."

- Beep It - Cornelius (2006): Also from the "Sensuous" album. More stop-motion madness with household objects.

Check out Koichiro Tsujikawa's homepage for more background info and links to other videos for Cornelius, as well as for UA, Rip Slyme, and more.

Ubiko robot knows where the smokers hang

21 Feb 2007

Ubiko sniffs out ashtrays -- Robot manufacturer tmsuk, Kyushu University and the Kanazawa Institute of Technology have teamed up to develop a robot that can sniff out the smells that accompany fire. A public demonstration of the robot's new abilities was held at Kyushu University on February 21.

The researchers outfitted a 60-kilogram (132-pound), 112-centimeter (44-inch) tall Ubiko -- a tmsuk robot originally designed to serve as a temporary receptionist -- with a first-of-a-kind set of olfactory sensors specifically tuned to detect the odors of smoke and ash.

In the test, Ubiko, which moves on wheels and has a slightly humanoid appearance (albeit with a pair of triangular feline ears atop its head), was tasked with patrolling four rooms, each with a different smell. One room smelled of perfume, one smelled of garlic, one smelled of cigarettes, and one was odorless. When the robot smelled the room with ashtrays, it identified it as likely to catch fire and sent a wireless message to security.

Kiyoshi Toko, electronic engineering professor at Kyushu University, says, "We want to increase the accuracy of the sensors and create a fire-prevention robot that can detect subtle smells that humans cannot perceive."

For now, the robot has no fire-fighting skills except the ability to alert the authorities when it detects a funny smell. This is probably a good thing in an office environment, for example, where Ubiko might wreak havoc by spraying fire retardant on heavy smokers or on innocent employees who happen to visit smoky restaurants during their lunch breaks.

[Source: Nikkei Net]

Time-lapse video of deep-sea feeding frenzy

16 Feb 2007

Deep-sea feeding frenzy ---

This video clip from NHK's "Planet Earth" shows the scene at dinner time on the deep ocean floor. The footage, which appears to have been shot by the Japanese submarine Shinkai 6500 in Okinawan waters at a depth of over 1500 meters (5,000 feet), shows sea-floor scavengers fighting for their piece of a fish carcass that has drifted down to the bottom. Crabs, eels and giant isopods (Bathynomus giganteus), which look like 30 centimeter (1 foot) long wood lice, join in the feeding frenzy that lasts several hours. Here it is time-lapsed to about 20 seconds for maximum impact. Itadakimasu.